Additional Information
| Product Name: | GST-USP11 |
|---|---|
| Also Known As: | UHX1 |
| Catalog No.: | H6110 |
| Size: | 25 µg |
| Molecular Weight: | 109.8 kDa |
| Species: | Human |
| Source: | Sf9 insect cells |
| Stock: | 20 mM Tris, 150 mM NaCl, 2 mM βME, 10% Glycerol |
| Concentration: | See tube label |
| Quality Assurance: | ~85% by SDS-PAGE, see datasheet for gel image |
| Storage: | Store at -80°C; avoid multiple freeze-thaw cycles |
| PDF Data Sheet: | PDF Datasheet， MSDS |
| NCBI RefSeq: | NM_004651 |
| Image(s): | H6110 image Coomassie Stained SDS-PAGE |
| Shipping Method: | Dry ice shipping |
| References: | 1. Wanson DA, et al. (1996) Hum Mol Genet 5, 533 – 538. 2. Ideguchi H, et al. (2002) Biochem J 367(Pt 1), 87 – 95. 3. Reyes-Turcu FE, et al.(2009) Annu Rev Biochem 78, 363 – 397. |
Details
Deubiquitinating enzymes (DUBs) are proteases that posses the ability to cleave ubiquitin chains or the isopeptide bond that conjugates ubiquitin with a substrate. Human cells have approximately 100 DUBs that play important roles in regulating various cellular events. Usp11 belongs to the ubiquitin-specific protease family. It helps in repairing DNA damage. It has been found to interact with RanBPM, a RanGTP-binding protein.
