Additional Information
| Product Name: | USP39 Rabbit pAb |
|---|---|
| Catalog No.: | Y9782-100 |
| Also Known As: | USP39; 65K; CGI-21; HSPC332; SAD1; SNRNP65 |
| Size: | 100 µl |
| Concentration: | See labels on tube |
| Host Species: | Rabbit |
| Isotype: | IgG |
| Reactivity: | Human, Mouse, Rat |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 336-565 of human USP39 (NP_006581.2). |
| Swiss Prot. #: | Q53GS9 |
| Calculated MW: | 65 kDa |
| Detected MW: | 65 kDa |
| Applications: | WB (1:500 - 1:2,000) IP (not tested) IHC (not tested) IF (not tested) Note: Antibody dilution should be optimized by users. |
| Purification: | Protein A or G affinity purification |
| Buffer: | PBS with 0.02% sodium azide, 50% glycerol, pH7.3 |
| Storage: | Store at -20℃. Centrifuge to maximize product recovery. |
| PDF Data Sheet: | PDF Datasheet， MSDS |
| Image(s): | (Click image to enlarge)  |
| Shipping Method: | Wet ice shipping |
| References: | 1. Makarova OV, et al. (2001) EMBO J 20, 2553 - 2563. 2. Agafonov DE, et al. (2016) Science 351, 1416 - 1420. |
Details
USP39 is a member of the USP subfamily of DUBs. DUBs are categorized into 5 subfamilies: USP, UCH, OTU, MJD, and JAMM. USP39 plays a role in pre-mRNA splicing as a component of the U4/U6-U5 tri-snRNP, one of the building blocks of the precatalytic spliceosome. Regulates AURKB mRNA levels, and thereby plays a role in cytokinesis and in the spindle checkpoint. Does not have ubiquitin-specific peptidase activity.
