Additional Information
| Product Name: | USP13 Rabbit pAb |
|---|---|
| Catalog No.: | Y9532-100 |
| Also Known As: | USP13; ISOT3; IsoT-3 |
| Size: | 100 µl |
| Concentration: | See labels on tube |
| Host Species: | Rabbit |
| Isotype: | IgG |
| Reactivity: | Human, Mouse, Rat |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 90-200 of human USP13 (NP_003931.2). |
| Swiss Prot. #: | Q92995 |
| Calculated MW: | 97 kDa |
| Detected MW: | 97 kDa |
| Applications: | WB (1:1000 - 1:2,000) IP (not tested) IHC (not tested) IF (not tested) Note: Antibody dilution should be optimized by users. |
| Purification: | Protein A or G affinity purification |
| Buffer: | PBS with 0.02% sodium azide, 50% glycerol, pH7.3 |
| Storage: | Store at -20℃. Centrifuge to maximize product recovery. |
| PDF Data Sheet: | PDF Datasheet， MSDS |
| Image(s): | (Click image to enlarge)  |
| Shipping Method: | Wet ice shipping |
| References: | 1. Nijman SM, et al. (2005) Cell 123, 773 - 786. 2. Liu J, et al. (2011) Cell 147, 223 - 234. |
Details
USP13 is a member of the USP subfamily of DUBs. DUBs are categorized into 5 subfamilies: USP, UCH, OTU, MJD, and JAMM. Studies show that USP13 plays a critical role in autophagy through deubiquitination of target proteins such as BECN1 and USP10. Research also suggests that USP13 is implicated in the pathogenesis of melanoma through its ability to regulate the ubiquitination status of MITF.
