Additional Information
| Product Name: | USP10 Rabbit mAb |
|---|---|
| Catalog No.: | Y9500-100 |
| Also Known As: | UBPO |
| Size: | 100 µl |
| Concentration: | See labels on tube |
| Host Species: | Rabbit |
| Isotype: | IgG |
| Reactivity: | Human, Mouse |
| Immunogen: | A synthesized peptide derived from human USP10. |
| Swiss Prot. #: | Q14694 |
| Calculated MW: | 87 kDa |
| Detected MW: | 110 kDa |
| Applications: | WB (1:500 - 1:2,000) IF (1:50 - 1:200) IP (not tested) IHC (not tested) Note: Antibody dilution should be optimized by users. |
| Purification: | Protein A or G affinity purification |
| Buffer: | PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3 |
| Storage: | Store at -20℃. Centrifuge to maximize product recovery. |
| PDF Data Sheet: | PDF Datasheet， MSDS |
| Image(s): | (Click image to enlarge)  |
| Shipping Method: | Wet ice shipping |
| References: | 1. Nagase T, et al. (1996) DNA Res 3, 17 - 24. 2. Soncini C, et al. (2001) Oncogene 20, 3869 - 3879. |
Details
USP10 is a member of the USP subfamily of DUBs. DUBs are categorized into 5 subfamilies: USP, UCH, OTU, MJD, and JAMM. USP10 specifically cleaves ubiquitin from ubiquitin-conjugated protein substrates. It functions as a co-factor of the DNA-bound androgen receptor complex, and is inhibited by a protein in the Ras-GTPase pathway.
