Additional Information
| Product Name: | UBR5 Rabbit pAb |
|---|---|
| Catalog No.: | Y6202-100 |
| Also Known As: | UBR5; DD5; EDD; EDD1; HYD |
| Size: | 100 µl |
| Concentration: | See labels on tube |
| Host Species: | Rabbit |
| Isotype: | IgG |
| Reactivity: | Human |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 550-760 of human UBR5 (NP_056986.2). |
| Swiss Prot. #: | O95071 |
| Calculated MW: | 309 kDa |
| Detected MW: | 300 kDa |
| Applications: | WB (1:500 - 1:2,000) IP (not tested) IHC (not tested) IF (not tested) Note: Antibody dilution should be optimized by users. |
| Purification: | Protein A or G affinity purification |
| Buffer: | PBS with 0.02% sodium azide, 50% glycerol, pH7.3 |
| Storage: | Store at -20℃. Centrifuge to maximize product recovery. |
| PDF Data Sheet: | PDF Datasheet， MSDS |
| Image(s): | (Click image to enlarge)  |
| Shipping Method: | Wet ice shipping |
| References: | 1. Callaghan MJ, et al. (1998) Oncogene 17, 3479 - 3491. 2. Sriram SM, et al. (2011) Nat Rev Mol Cell Biol 12, 735 - 747. |
Details
UBR5 is a HECT domain-containing ubiquitin E3 ligase of the N-end rule pathway that promotes the ubiquitination and proteasomal degradation of proteins harboring N-degrons.
