Additional Information
| Product Name: | WWP2 Rabbit pAb |
|---|---|
| Catalog No.: | Y6192-100 |
| Also Known As: | WWP2; AIP2; WWp2-like |
| Size: | 100 µl |
| Concentration: | See labels on tube |
| Host Species: | Rabbit |
| Isotype: | IgG |
| Reactivity: | Human |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 151-400 of human WWP2 (NP_001257383.1). |
| Swiss Prot. #: | O00308 |
| Calculated MW: | 98 kDa |
| Detected MW: | 105 kDa |
| Applications: | WB (1:500 - 1:2,000) IP (not tested) IHC (not tested) IF (not tested) Note: Antibody dilution should be optimized by users. |
| Purification: | Protein A or G affinity purification |
| Buffer: | PBS with 0.02% sodium azide, 50% glycerol, pH7.3 |
| Storage: | Store at -20℃. Centrifuge to maximize product recovery. |
| PDF Data Sheet: | PDF Datasheet， MSDS |
| Image(s): | (Click image to enlarge)  |
| Shipping Method: | Wet ice shipping |
| References: | 1. Pirozzi G, et al. (1997) J Biol Chem 272, 14611 - 14616. 2. Li H, et al. (2018) J Biol Chem 293, 8886 - 8899. |
Details
WWP2 is a member of the Nedd4 family of E3 ligases. WWP2 contains four WW domains and may play a role in multiple processes including chondrogenesis and the regulation of oncogenic signaling pathways via interactions with Smad proteins and the tumor suppressor PTEN.
