Additional Information
| Product Name: | ANAPC5 Rabbit pAb |
|---|---|
| Catalog No.: | Y6372-100 |
| Also Known As: | ANAPC5; APC5 |
| Size: | 100 µl |
| Concentration: | See labels on tube |
| Host Species: | Rabbit |
| Isotype: | IgG |
| Reactivity: | Human, Mouse, Rat |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-250 of human ANAPC5 (NP_057321.2). |
| Swiss Prot. #: | Q9UJX4 |
| Calculated MW: | 85 kDa |
| Detected MW: | 85 kDa |
| Applications: | WB (1:500 - 1:2,000) IP (1:50 - 1:100) IHC (1:50 - 1:200) IF (not tested) Note: Antibody dilution should be optimized by users. |
| Purification: | Protein A or G affinity purification |
| Buffer: | PBS with 0.02% sodium azide, 50% glycerol, pH7.3 |
| Storage: | Store at -20℃. Centrifuge to maximize product recovery. |
| PDF Data Sheet: | PDF Datasheet， MSDS |
| Image(s): | (Click image to enlarge)  |
| Shipping Method: | Wet ice shipping |
| References: | 1. Jorgensen PM, et al. (2001) Gene, 262, 51 - 59. 2. Turnell AS, et al. (2005) Nature 438, 690 - 695. |
Details
ANAPC5 is a subunit of the anaphase-promoting complex (APC), which functions at the metaphase-to-anaphase transition of the cell cycle and is regulated by spindle checkpoint proteins. The APC is an E3 ubiquitin ligase that targets cell cycle regulatory proteins for degradation by the proteasome, thereby allowing progression through the cell cycle.
