Additional Information
| Product Name: | GST-DESI-2 |
|---|---|
| Also Known As: | PPPDE1 |
| Catalog No.: | H8970 |
| Size: | 50 µg |
| Molecular Weight: | 21.4 kDa (no GST tag) |
| Species: | Human |
| Source: | E. coli |
| Stock: | 20 mM Tris, 150 mM NaCl, 2 mM βME, 10% Glycerol |
| Concentration: | See tube label |
| Quality Assurance: | ~90% by SDS-PAGE, see datasheet for gel image |
| Storage: | Store at -80°C; avoid multiple freeze-thaw cycles |
| PDF Data Sheet: | PDF Datasheet， MSDS |
| NCBI RefSeq: | NM_016076.4 |
| Image(s): | H8970 image Coomassie stained SDS-PAGE of 5 ug GST-DESI-2. |
| Shipping Method: | Dry ice shipping |
| References: | 1. Iyer LM., et al. Cell cycle 3 (2004) 1440e1450. 2. Shin EJ., et al. EMBO Rep. 13 (2012) 339e346. 3. Gillies J., et al., EMBO Rep. 13 (2012) 284e285. 4. Xie X., et al. Biochem Biophys Res Commun. 2017 488(2):291-296. |
Details
DESI-2 (desumoylating isopeptidase 2, also called Permuted Papain fold Peptidases of DsRNA viruses and Eukaryotes (PPPDE1)) and DESI-1 (also called PPPDE2) contain a Ub-binding domain and a cysteine protease domain. They catalyze both desumolyating and deubiquitinating activities.
