Additional Information
| Product Name: | Nigericin Sodium Salt |
|---|---|
| Also Known As: | Antibiotic K178 |
| Catalog No.: | F3200-5 |
| Size: | 5 mg |
| CAS: | 28643-80-3 |
| Formula: | C40H67O11Na |
| Molecular Weight: | 746.94 g/mol |
| Form: | Powder |
| Quality Assurance: | >95% by NMR |
| Source: | Streptomyces hygroscopicus |
| Storage: | Eligible for room temperature shipping. Store at -20°C upon receiving; protect from air and light. |
| PDF Data Sheet: | Download PDF datasheet, MSDS |
| Image(s): | N/A |
| Shipping Method: | Room temperature shipping |
| References: | 1. Eytan, et al (1990) J. Biol. Chem., 22, 12949. |
Details
Nigericin sodium salt is an antibiotic derived from Streptomyces hygroscopicus. Functions as an H+, K+, and Pb2+ ionophore. Disrupts mitochondrial membrane potential and activates the NLRP3 inflammasome to induce inflammation.
