Additional Information
Product Name: | Nigericin Sodium Salt |
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Also Known As: | Antibiotic K178 |
Catalog No.: | F3200-25 |
Size: | 25 mg |
CAS: | 28643-80-3 |
Formula: | C40H67O11Na |
Molecular Weight: | 746.94 g/mol |
Form: | Powder |
Quality Assurance: | >95% by NMR |
Source: | Streptomyces hygroscopicus |
Storage: | Eligible for room temperature shipping. Store at -20°C upon receiving; protect from air and light. |
PDF Data Sheet: | Download PDF datasheet, MSDS |
Image(s): | N/A |
Shipping Method: | Room temperature shipping |
References: | 1. Eytan, et al (1990) J. Biol. Chem., 22, 12949. |
Details
Nigericin sodium salt is an antibiotic derived from Streptomyces hygroscopicus. Functions as an H+, K+, and Pb2+ ionophore. Disrupts mitochondrial membrane potential and activates the NLRP3 inflammasome to induce inflammation.