Additional Information
| Product Name: | USP4 Rabbit pAb |
|---|---|
| Catalog No.: | Y9432-100 |
| Also Known As: | USP4; UNP; Unph |
| Size: | 100 µl |
| Concentration: | See labels on tube |
| Host Species: | Rabbit |
| Isotype: | IgG |
| Reactivity: | Human, Mouse, Rat |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 560-700 of human USP4 (NP_003354.2 |
| Swiss Prot. #: | Q13107 |
| Calculated MW: | 108 kDa |
| Detected MW: | 95 kDa |
| Applications: | WB (1:500 - 1:2,000) IF (1:50 - 1:200) IP (not tested) IHC (not tested) Note: Antibody dilution should be optimized by users. |
| Purification: | Protein A or G affinity purification |
| Buffer: | PBS with 0.02% sodium azide, 50% glycerol, pH7.3 |
| Storage: | Store at -20℃. Centrifuge to maximize product recovery. |
| PDF Data Sheet: | PDF Datasheet， MSDS |
| Image(s): | (Click image to enlarge)  |
| Shipping Method: | Wet ice shipping |
| References: | 1. Gupta K, et al. (1993) Oncogene 8, 2307 - 2310. 2. Gilchrist CA, et al. (1997) J Biol Chem 272 (51), 32280 32285. |
Details
USP4 is a member of the USP subfamily of DUBs. DUBs are categorized into 5 subfamilies: USP, UCH, OTU, MJD, and JAMM. USP4 has substrates with important function in a number of cell signalling pathways, including the NF-κB, TGF-β, Wnt/β-catenin, p53, and spliceosome pathways. Other substrates include the adenosine A2A receptor and the Ro52 (TRIM21) protein.
