Additional Information
| Product Name: | USP28 Rabbit pAb |
|---|---|
| Catalog No.: | Y9672-100 |
| Also Known As: | USP28 |
| Size: | 100 µl |
| Concentration: | See labels on tube |
| Host Species: | Rabbit |
| Isotype: | IgG |
| Reactivity: | Human, Mouse |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 430-580 of human USP28 (NP_065937.1). |
| Swiss Prot. #: | Q96RU2 |
| Calculated MW: | 122 kDa |
| Detected MW: | 110 kDa |
| Applications: | WB (1:500 - 1:2,000) IP (not tested) IHC (not tested) IF (not tested) Note: Antibody dilution should be optimized by users. |
| Purification: | Protein A or G affinity purification |
| Buffer: | PBS with 0.02% sodium azide, 50% glycerol, pH7.3 |
| Storage: | Store at -20℃. Centrifuge to maximize product recovery. |
| PDF Data Sheet: | PDF Datasheet， MSDS |
| Image(s): | (Click image to enlarge)  |
| Shipping Method: | Wet ice shipping |
| References: | 1. Nijman SM, et al. (2005) Cell 123, 773 - 786. 2. Zhang D, et al. (2006) Cell 126, 529 - 542. |
Details
USP28 is a member of the USP subfamily of DUBs. DUBs are categorized into 5 subfamilies: USP, UCH, OTU, MJD, and JAMM. USP28 can deubiquinate several target proteins in DNA-damage pathway, resulting in their stability, including p53BP1 and Chk2. USP28 also plays an important role in Myc related signaling by binding through FBW7α to Myc.
