Additional Information
| Product Name: | UBE2D1 Rabbit pAb |
|---|---|
| Catalog No.: | Y3232-100 |
| Also Known As: | UBE2D1; E2(17)KB1; SFT; UBC4/5; UBCH5; UBCH5A |
| Size: | 100 µl |
| Concentration: | See labels on tube |
| Host Species: | Rabbit |
| Isotype: | IgG |
| Reactivity: | Human, Mouse, Rat |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-147 of human UBE2D1. |
| Swiss Prot. #: | P51668 |
| Calculated MW: | 16 kDa |
| Detected MW: | 14 kDa |
| Applications: | WB (1:500 - 1:2,000) IHC (1:50 - 1:200) IP (not tested) IF (not tested) Note: Antibody dilution should be optimized by users. |
| Purification: | Protein A or G affinity purification |
| Buffer: | PBS with 0.02% sodium azide, 50% glycerol, pH7.3 |
| Storage: | Store at -20℃. Centrifuge to maximize product recovery. |
| PDF Data Sheet: | PDF Datasheet， MSDS |
| Image(s): | (Click image to enlarge)  |
| Shipping Method: | Wet ice shipping |
| References: | 1. Scheffner M, et al. (1994) Proc Natl Acad Sci USA 91, 8797 - 8801. 2. Huibregtse JM, et al. (1995) Proc Natl Acad Sci USA 92(7), 2563 - 2567. |
Details
UBE2D1 is a member of the E2 ubiquitin-conjugating enzyme family. Accepts ubiquitin from E1and catalyzes its covalent attachment to other proteins. This enzyme is closely related to a stimulator of iron transport (SFT), and is up-regulated in hereditary hemochromatosis. It also functions in the ubiquitination of the tumor-suppressor protein p53 and the hypoxia-inducible transcription factor HIF1alpha by interacting with the E1 ubiquitin-activating enzyme and the E3 ubiquitin-protein ligases.
