Additional Information
| Product Name: | UBE2C Rabbit pAb |
|---|---|
| Catalog No.: | Y3222-100 |
| Also Known As: | UBE2C; UBCH10; dJ447F3.2 |
| Size: | 100 µl |
| Concentration: | See labels on tube |
| Host Species: | Rabbit |
| Isotype: | IgG |
| Reactivity: | Human |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-179 of human UBE2C. |
| Swiss Prot. #: | O00762 |
| Calculated MW: | 20 kDa |
| Detected MW: | 20 kDa |
| Applications: | WB (1:500 - 1:2,000) IP (1:20 - 1:50) IHC (1:50 - 1:200) IF (1:50 - 1:100) Note: Antibody dilution should be optimized by users. |
| Purification: | Protein A or G affinity purification |
| Buffer: | PBS with 0.02% sodium azide, 50% glycerol, pH7.3 |
| Storage: | Store at -20℃. Centrifuge to maximize product recovery. |
| PDF Data Sheet: | PDF Datasheet， MSDS |
| Image(s): | (Click image to enlarge)  |
| Shipping Method: | Wet ice shipping |
| References: | 1. Hershko A, et al. (1994) J Biol CHem 269, 4940 - 4946. 2. Aristarkhov A, et al. (1996) Proc Natl Acad Sci USA 93(9), 4294 - 4299. |
Details
UBE2C is a member of the E2 ubiquitin-conjugating enzyme family. Accepts ubiquitin from E1 and catalyzes its covalent attachment to other proteins. UBE2C is one of several ubiquitin conjugating enzymes participating in the E3 anaphase-promoting complex (APC/C). UBE2C is involved in the control of multiple stages of the cell cycle including inactivation of the mitotic spindle assembly checkpoint.
