Additional Information
| Product Name: | RNF125 Rabbit pAb |
|---|---|
| Catalog No.: | Y6062-100 |
| Also Known As: | RNF125; TNORS; TRAC-1; TRAC1 |
| Size: | 100 µl |
| Concentration: | See labels on tube |
| Host Species: | Rabbit |
| Isotype: | IgG |
| Reactivity: | Human |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-105 of human RNF125 (NP_060301.2). |
| Swiss Prot. #: | Q96EQ8 |
| Calculated MW: | 26 kDa |
| Detected MW: | 26 kDa |
| Applications: | WB (1:500 - 1:2,000) IP (not tested) IHC (not tested) IF (not tested) Note: Antibody dilution should be optimized by users. |
| Purification: | Protein A or G affinity purification |
| Buffer: | PBS with 0.02% sodium azide, 50% glycerol, pH7.3 |
| Storage: | Store at -20℃. Centrifuge to maximize product recovery. |
| PDF Data Sheet: | PDF Datasheet， MSDS |
| Image(s): | (Click image to enlarge)  |
| Shipping Method: | Wet ice shipping |
| References: | 1. Zhao H, et al. (2005) J Immun 174, 5288 - 5297. 2. Giannini AL, et al. (2008)Biochem J 410, 101 - 111. |
Details
RNF125 is an E3 ubiquitin ligase that contains a RING finger domain in the N-terminus and three zinc-binding and one ubiquitin-interacting motif in the C-terminus. As a result of myristoylation, this protein associates with membranes and is primarily localized to intracellular membrane systems. It may function as a positive regulator in the T-cell receptor signaling pathway.
