Additional Information
| Product Name: | OTUD7A Rabbit pAb |
|---|---|
| Catalog No.: | Y9122-100 |
| Also Known As: | OTUD7A; C15orf16; C16ORF15; CEZANNE2; OTUD7 |
| Size: | 100 µl |
| Concentration: | See labels on tube |
| Host Species: | Rabbit |
| Isotype: | IgG |
| Reactivity: | Human |
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 800-900 of mouse OTUD7A (NP_570950.1). |
| Swiss Prot. #: | Q8TE49 |
| Calculated MW: | 100 kDa |
| Detected MW: | 105 kDa |
| Applications: | WB (1:500 - 1:2,000) IP (not tested) IHC (not tested) IF (not tested) Note: Antibody dilution should be optimized by users. |
| Purification: | Protein A or G affinity purification |
| Buffer: | PBS with 0.02% sodium azide, 50% glycerol, pH7.3 |
| Storage: | Store at -20℃. Centrifuge to maximize product recovery. |
| PDF Data Sheet: | PDF Datasheet， MSDS |
| Image(s): | (Click image to enlarge)  |
| Shipping Method: | Wet ice shipping |
| References: | 1. Kayagaki N, et al. (2007) Science 318, 1628 - 1632. 2. Uddin M, et al. (2018) Am J Hum Genet 102, 278 - 295. |
Details
OTUD7A is a member of OTU family of DUBs. DUBs are categorized into 5 subfamilies: USP, UCH, OTU, MJD, and JAMM. OTUD7A prefers to cleave lysine 11-linked polyubiqutin chains, acts on TNF receptor associated factor 6 (TRAF6) to control nuclear factor kappa B expression. OTUD7A also localizes to the postsynaptic density in the brain, suggesting a role in synapse development and maturation.
