Additional Information
| Product Name: | HERC4 Rabbit pAb |
|---|---|
| Catalog No.: | Y5812-100 |
| Also Known As: | HERC4 |
| Size: | 100 µl |
| Concentration: | See labels on tube |
| Host Species: | Rabbit |
| Isotype: | IgG |
| Reactivity: | Human, Mouse, Rat |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 400-700 of human HERC4 (NP_056416.2). |
| Swiss Prot. #: | Q5GLZ8 |
| Calculated MW: | 118 kDa |
| Detected MW: | 118 kDa |
| Applications: | WB (1:500 - 1:2,000) IP (not tested) IHC (not tested) IF (not tested) Note: Antibody dilution should be optimized by users. |
| Purification: | Protein A or G affinity purification |
| Buffer: | PBS with 0.02% sodium azide, 50% glycerol, pH7.3 |
| Storage: | Store at -20℃. Centrifuge to maximize product recovery. |
| PDF Data Sheet: | PDF Datasheet， MSDS |
| Image(s): | (Click image to enlarge)  |
| Shipping Method: | Wet ice shipping |
| References: | 1. Nagase T, et al. (2000) DNA Res 7, 273 - 281. 2. Hochrainer K, et al. (2005) Genomics 85, 153 - 164. |
Details
HERC4 belongs to the HERC family of ubiquitin ligases, all of which contain a HECT domain and at least one RCC1-like domain (RLD). The 350-amino acid HECT domain is predicted to catalyze the formation of a thioester with ubiquitin before transferring it to a substrate, and the RLD is predicted to act as a guanine nucleotide exchange factor for small G proteins.
