Additional Information
| Product Name: | FBXW5 Rabbit pAb |
|---|---|
| Catalog No.: | Y5702-100 |
| Also Known As: | FBXW5; Fbw5 |
| Size: | 100 µl |
| Concentration: | See labels on tube |
| Host Species: | Rabbit |
| Isotype: | IgG |
| Reactivity: | Human |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 184-566 of human FBXW5 (NP_061871.1). |
| Swiss Prot. #: | Q969U6 |
| Calculated MW: | 63 kDa |
| Detected MW: | 72 kDa |
| Applications: | WB (1:200 - 1:1,000) IP (not tested) IHC (not tested) IF (not tested) Note: Antibody dilution should be optimized by users. |
| Purification: | Protein A or G affinity purification |
| Buffer: | PBS with 0.02% sodium azide, 50% glycerol, pH7.3 |
| Storage: | Store at -20℃. Centrifuge to maximize product recovery. |
| PDF Data Sheet: | PDF Datasheet， MSDS |
| Image(s): | (Click image to enlarge)  |
| Shipping Method: | Wet ice shipping |
| References: | 1. Winston JT, et al. (1999) Curr Biol 9, 1180 - 1182. 2. Hu J, et al. (2008) Genes Dev 22, 866 - 871. |
Details
FBXW5 is a member of the Fbws class of the F-box protein family. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complexes called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into three classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs.
