Additional Information
| Product Name: | CDC20 Rabbit pAb |
|---|---|
| Catalog No.: | Y6452-100 |
| Also Known As: | CDC20; CDC20A; bA276H19.3; p55CDC |
| Size: | 100 µl |
| Concentration: | See labels on tube |
| Host Species: | Rabbit |
| Isotype: | IgG |
| Reactivity: | Human, Mouse, Rat |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-270 of human CDC20 (NP_001246.2). |
| Swiss Prot. #: | Q12834 |
| Calculated MW: | 54 kDa |
| Detected MW: | 54 kDa |
| Applications: | WB (1:500 - 1:2,000) IP (1:50 - 1:200) IHC (1:50 - 1:100) IF (not tested) Note: Antibody dilution should be optimized by users. |
| Purification: | Protein A or G affinity purification |
| Buffer: | PBS with 0.02% sodium azide, 50% glycerol, pH7.3 |
| Storage: | Store at -20℃. Centrifuge to maximize product recovery. |
| PDF Data Sheet: | PDF Datasheet， MSDS |
| Image(s): | (Click image to enlarge)  |
| Shipping Method: | Wet ice shipping |
| References: | 1. Weinstein J, et al. (1994) Mol Cell Biol 14, 3350 - 3363. 2. Fang G, et al. (1998) Genes Dev 12, 1871 - 1883. |
Details
CDC20 appears to act as a regulatory protein interacting with several other proteins at multiple points in the cell cycle. CDC20 is required for full ubiquitin ligase activity of the anaphase promoting complex/cyclosome (APC/C) and may confer substrate specificity upon the complex.
