Additional Information
| Product Name: | Beta-TRCP Rabbit pAb |
|---|---|
| Catalog No.: | Y6242-100 |
| Also Known As: | BTRC; BETA-TRCP; FBW1A; FBXW1; FBXW1A; FWD1; bTrCP; bTrCP1; betaTrCP; Beta-TRCP |
| Size: | 100 µl |
| Concentration: | See labels on tube |
| Host Species: | Rabbit |
| Isotype: | IgG |
| Reactivity: | Human, Mouse, Rat |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 50-340 of human Beta-TRCP (NP_378663.1). |
| Swiss Prot. #: | Q9Y297 |
| Calculated MW: | 68 kDa |
| Detected MW: | 65 kDa |
| Applications: | WB (1:500 - 1:2,000) IHC (1:50 - 1:200) IF (1:50 - 1:100) IP (not tested) Note: Antibody dilution should be optimized by users. |
| Purification: | Protein A or G affinity purification |
| Buffer: | PBS with 0.02% sodium azide, 50% glycerol, pH7.3 |
| Storage: | Store at -20℃. Centrifuge to maximize product recovery. |
| PDF Data Sheet: | PDF Datasheet， MSDS |
| Image(s): | (Click image to enlarge)  |
| Shipping Method: | Wet ice shipping |
| References: | 1. Margottin F, et al. (1998) Mol Cell 1, 565 - 574. 2. Bour S, et al. (2001) J Biol Chem 276, 15920 - 15928. |
Details
BTRC is a substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Recognizes and binds to phosphorylated target proteins.
