Additional Information
| Product Name: | LCL161 |
|---|---|
| Also Known As: | CAS# 1005342-46-0 |
| Catalog No.: | F7171-5 |
| Size: | 5 mg |
| Molecular Weight: | 500.63 g/mol |
| Species: | N/A |
| Source: | Synthetic |
| Stock: | Powder |
| Concentration: | N/A |
| Quality Assurance: | >98% by HPLC and NMR |
| Storage: | Eligible for room temperature shipping. Store at -20°C upon receiving; protect from air and ligh |
| PDF Data Sheet: | Download PDF datasheet， MSDS |
| NCBI RefSeq: | N/A |
| Image(s): | No |
| Shipping Method: | Room temperature shipping |
| References: | 1. Chen K F., et al. (2012) Biochemical Pharmacology. 84, 268 2. Houghton P J., et al. (2012) Pediatric Blood & Cancer., 58, 636 |
Details
LCL161 is a potent Smac mimetic that inhibits the inhibitor of apoptosis proteins XIAP, cIAP-1 and c-IAP2. LCL161 induces caspase-dependent apoptosis in various cancer cell lines.
