Products
- RELAYTR FRET Reagents & Kits
- Proteasomes / Activators / Subunits
- E1 Activating Enzymes
- E2 Conjugating Enzymes
- E3 Ubiquitin Ligases
- Polyubiquitin / PolySUMO Chains
- Ubiquitin / Ubiquitin-like Proteins / Mutants
- Deubiquitinating Enzymes
- Inhibitors
- Fluorescent Peptide / Protein Substrates
- Ubiquitin Binding Proteins
- Ubiquitin / UBL Derivatives
- Apoptosis / Necrosis
- Antibodies
- Kits
- Protein Expression / Purification Reagents
- DNA / Protein Ladders
- Covid-19 Research
TR-FRET Assay Service
Customized TR-FRET reagent and assay development using in-house developed terbium/europium chelate-based (donor) and fluorescein/Cy5-based (acceptor) covalent modifiers. Both donors and acceptors can be conjugated onto substance of interest via either free thiols (cysteines) or amines (lysines).
Contact us to start your TR-FRET reagent/assay development!
Step 1. Sending us a service request with a brief project description.
Step 2. Meeting with us to introduce the project goal.
Step 3. Discussing and finalizing reagent and assay design.
Step 4. Reagent production.
Step 5. High throughput assay development (optional).
Step 6. Transferring reagent/assay.
Step 7. Follow-up customer support.
Toolbox For Degrader Development
- Versatile TR-FRET assays monitoring molecular proximity, protein abundance, enzyme activity, and posttranslational modifications (such as ubiquitination).
- Empowered by both terbium/fluorescein and europium/Cy5 pairs.
- Kits for assessing E3 ubiquitin ligase activity and profiling the E2 panel.
- TR-FRET capable tag antibodies for monitoring molecular proximity and protein abundance.
