Additional Information
| Product Name: | Dabcyl-KTSAVLQSGFRKME-Edans | ||
|---|---|---|---|
| Also Known As: | Dabcyl-KTSAVLQSGFRKME-Edans, Dabcyl-KTSAVLQSGFRKME-Edans.TFA, Dabcyl-Lys-Thr-Ser-Ala-Val-Leu-Gln-Ser-Gly-Phe-Arg-Lys-Met-Glu-Edans, or Dabcyl-Lys-Thr-Ser-Ala-Val-Leu-Gln-Ser-Gly-Phe-Arg-Lys-Met-Glu-Edans trifluoroacetate | ||
| Catalog No.: | V1010-1 | ||
| Size: | 1 mg | ||
| Molecular Weight: | 2081.5 Da | ||
| Species: | N/A | ||
| Source: | Synthetic | ||
| Stock: | Powder | ||
| Concentration: | N/A | ||
| Quality Assurance: | >95% by HPLC | ||
| Storage: | Eligible for room temperature shipping. Store at -20°C upon receiving; avoid multiple freeze-thaw cycles after dissolving in DMSO. Protect from light. | ||
| PDF Data Sheet: | Download PDF datasheet, MSDS | ||
| NCBI RefSeq: | N/A | ||
| Image(s): | (Click image to enlarge)
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| Shipping Method: | Room temperature shipping | ||
| References: | No |
Details
Dabcyl-KTSAVLQSGFRKME-Edans is an internally quenched fluorogenic substrate for the SARS-CoV family 3C-like protease (3CLP, also called main protease or MPro) with a Km value of 17 uM. Upon 3CLP-mediated cleavage between glutamine and serine, the resulting SGFRKME-EDANS fluorescence can be monitored at the excitation/emission wavelengths of 355/538 nm, respectively.
The working concentration is 20-50 µM.
