Additional Information
| Product Name: | GST-USP4 | ||
|---|---|---|---|
| Also Known As: | UNP; Unph | ||
| Catalog No.: | H5410 | ||
| Size: | 50 µg | ||
| Molecular Weight: | 108.6 kDa | ||
| Species: | Human | ||
| Source: | Bacterial recombinant | ||
| Stock: | 20 mM Tris, 150 mM NaCl, 2 mM βME, 10% Glycerol | ||
| Concentration: | See tube label | ||
| Quality Assurance: | ~ 75% by SDS-PAGE, see datasheet for gel image | ||
| Storage: | Store at -80°C; avoid multiple freeze-thaw cycles | ||
| PDF Data Sheet: | PDF Datasheet， MSDS | ||
| NCBI RefSeq: | NM_003363.3 | ||
| Image(s): |
Images:
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| Shipping Method: | Dry ice shipping | ||
| References: | 1. Wang L, et al. (2013) J Virol. 87(8):4507-15. 2. Zhang L, et al. (2012) Nat Cell Biol. 14(7):717-26. 3. Xiao N, et al. (2012) Biochem J. 441(3):979-86. |
Details
Usp4 is a member of the ubiquitin-specific protease family of deubiquitinating enzyme. A number of substrates of Usp4 have been identified, including TRIM21, TRAF2, TRAF6, RIG-1, RIP1, PDK1, TAK1 and etc. Usp4-mediated deubiquitination was found to regulate several signaling pathways, including the AKT signaling, RIG-1-mediated antiviral response, TNFα-induced signaling, and the Wnt signaling.
Images:
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Coomassie-stained SDS-PAGE Lane 1: Molecular weight markers Lane 2: 5 µg purified GST-USP4 |
