Additional Information
| Product Name: | USP24 Rabbit pAb |
|---|---|
| Catalog No.: | Y9632-100 |
| Also Known As: | USP24 |
| Size: | 100 µl |
| Concentration: | See labels on tube |
| Host Species: | Rabbit |
| Isotype: | IgG |
| Reactivity: | Human, Mouse |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 2431-2620 of human USP24 (NP_056121.2). |
| Swiss Prot. #: | Q9UPU5 |
| Calculated MW: | 294 kDa |
| Detected MW: | 294 kDa |
| Applications: | WB (1:500 - 1:2,000) IP (not tested) IHC (not tested) IF (not tested) Note: Antibody dilution should be optimized by users. |
| Purification: | Protein A or G affinity purification |
| Buffer: | PBS with 0.02% sodium azide, 50% glycerol, pH7.3 |
| Storage: | Store at -20℃. Centrifuge to maximize product recovery. |
| PDF Data Sheet: | PDF Datasheet， MSDS |
| Image(s): | (Click image to enlarge)  |
| Shipping Method: | Wet ice shipping |
| References: | 1. Kikuno R, et al. (1999) DNA Res 6, 197 - 205. 2. Zhang L, et al. (2012) Cell Cycle 11, 4378 - 4384. |
Details
USP24 is a member of the USP subfamily of DUBs. DUBs are categorized into 5 subfamilies: USP, UCH, OTU, MJD, and JAMM. USP24 regulates cell survival in various contexts through modulating the protein stability of some of its substrates including DDB2, MCL1 or TP53. Plays a positive role on ferritinophagy where ferritin is degraded in lysosomes and releases free iron.
