Additional Information
| Product Name: | UBE2V2 Rabbit pAb |
|---|---|
| Catalog No.: | Y3452-100 |
| Also Known As: | UBE2V2; DDVIT1; DDVit-1; EDAF-1; EDPF-1; EDPF1; MMS2; UEV-2; UEV2 |
| Size: | 100 µl |
| Concentration: | See labels on tube |
| Host Species: | Rabbit |
| Isotype: | IgG |
| Reactivity: | Human, Mouse, Rat |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-145 of human UBE2V2. |
| Swiss Prot. #: | Q15819 |
| Calculated MW: | 16 kDa |
| Detected MW: | 16 kDa |
| Applications: | WB (1:500 - 1:2,000) IHC (1:50 - 1:200) IP (not tested) IF (not tested) Note: Antibody dilution should be optimized by users. |
| Purification: | Protein A or G affinity purification |
| Buffer: | PBS with 0.02% sodium azide, 50% glycerol, pH7.3 |
| Storage: | Store at -20℃. Centrifuge to maximize product recovery. |
| PDF Data Sheet: | PDF Datasheet， MSDS |
| Image(s): | (Click image to enlarge)  |
| Shipping Method: | Wet ice shipping |
| References: | 1. Fritsche J, et al. (1997) Biochem Biophys Res Commun 235(2), 407 - 412. 2. Xiao W, et al. (1998) Nucleic Acids Res 26, 3908 - 3914. |
Details
UBE2V2 is a ubiquitin‐conjugating enzyme variant. It has no ubiquitin ligase activity on its own. The UBE2V2/UBE2N heterodimer catalyzes the synthesis of non-canonical poly-ubiquitin chains that are linked through 'Lys-63'. This type of poly-ubiquitination does not lead to protein degradation by the proteasome. Mediates transcriptional activation of target genes. Plays a role in the control of progress through the cell cycle and differentiation.
