Additional Information
| Product Name: | TRIM63 Rabbit pAb |
|---|---|
| Catalog No.: | Y6152-100 |
| Also Known As: | TRIM63; IRF; MURF1; MURF2; RNF28; SMRZ |
| Size: | 100 µl |
| Concentration: | See labels on tube |
| Host Species: | Rabbit |
| Isotype: | IgG |
| Reactivity: | Human, Mouse, Rat |
| Immunogen: | A synthetic peptide of human TRIM63. |
| Swiss Prot. #: | Q969Q1 |
| Calculated MW: | 40 kDa |
| Detected MW: | 40 kDa |
| Applications: | WB (1:500 - 1:2,000) IF (1:50 - 1:200) IP (not tested) IHC (not tested) Note: Antibody dilution should be optimized by users. |
| Purification: | Protein A or G affinity purification |
| Buffer: | PBS with 0.02% sodium azide, 50% glycerol, pH7.3 |
| Storage: | Store at -20℃. Centrifuge to maximize product recovery. |
| PDF Data Sheet: | PDF Datasheet， MSDS |
| Image(s): | (Click image to enlarge)  |
| Shipping Method: | Wet ice shipping |
| References: | 1. Dai KS and Liew CC, (2001) J Biol Chem 276, 23992 - 23999. 2. Bodine SC, et al. (2001) Science 294, 1704 - 1708. |
Details
TRIM63 is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. TRIM63 is an E3 ubiquitin ligase that promotes muscle cell protein degradation during muscle atrophy.
