Additional Information
| Product Name: | TRIM2 Rabbit pAb |
|---|---|
| Catalog No.: | Y6092-100 |
| Also Known As: | TRIM2; CMT2R; RNF86 |
| Size: | 100 µl |
| Concentration: | See labels on tube |
| Host Species: | Rabbit |
| Isotype: | IgG |
| Reactivity: | Mouse, Rat |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 100-300 of human TRIM2 (NP_056086.2). |
| Swiss Prot. #: | Q9C040 |
| Calculated MW: | 84 kDa |
| Detected MW: | 81 kDa |
| Applications: | WB (1:500 - 1:2,000) IP (not tested) IHC (not tested) IF (not tested) Note: Antibody dilution should be optimized by users. |
| Purification: | Protein A or G affinity purification |
| Buffer: | PBS with 0.02% sodium azide, 50% glycerol, pH7.3 |
| Storage: | Store at -20℃. Centrifuge to maximize product recovery. |
| PDF Data Sheet: | PDF Datasheet， MSDS |
| Image(s): | (Click image to enlarge)  |
| Shipping Method: | Wet ice shipping |
| References: | 1. Balastik M, et al. (2008) Proc Nat Acad Sci USA 105, 12016 - 12021. 2. Thompson S, et al. (2011) J Biol Chem 286, 19331 - 19339. |
Details
TRIM2 is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. It plays a neuroprotective role and functions as an E3-ubiquitin ligase in proteasome-mediated degradation of target proteins.
