Additional Information
| Product Name: | NEK7 Rabbit mAb |
|---|---|
| Catalog No.: | Z5840-20 |
| Also Known As: | NEK7 |
| Size: | 20 µl |
| Concentration: | See labels on tube |
| Host Species: | Rabbit |
| Isotype: | IgG |
| Reactivity: | Human,Mouse,Rat |
| Immunogen: | A synthesized peptide derived from human NEK7. |
| Swiss Prot. #: | Q8TDX7 |
| Calculated MW: | 35kDa |
| Detected MW: | 32KDa |
| Applications: | WB (1:500 - 1:2,000) IP (not tested) IHC (not tested) IF (not tested) Note: Antibody dilution should be optimized by users. |
| Purification: | Protein A or G affinity purification |
| Buffer: | PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3. |
| Storage: | Store at -20℃. Avoid freeze / thaw cycles. |
| PDF Data Sheet: | PDF Datasheet， MSDS |
| Image(s): | (Click image to enlarge)  |
| Shipping Method: | Wet ice shipping |
| References: | 1. Kimura M and Okano Y, (2001) Cytogenet Cell Genet 94, 33-38. 2. Belham C, et al. (2001) Curr Biol 11, 1155-1167. |
Details
NEK7 is a member of NEK Ser/Thr protein kinase family. The NEK family of protein kinases is composed of 11 members in humans that share an amino-terminal catalytic domain related to NIMA, a serine/threonine kinase identified in Aspergillus nidulans. It plays an important role in mitotic cell cycle progression and required for microtubule nucleation activity of the centrosome, robust mitotic spindle formation and cytokinesis. NEK6/7 have been suggested to phosphorylate and activate p70 S6 kinase in vitro.
