UBE2A Rabbit pAb

UBE2A is a member of the E2 ubiquitin-conjugating enzyme family. Accepts ubiquitin from E1 and catalyzes its covalent attachment to other proteins. In association with the E3 enzyme BRE1 (RNF20 and/or RNF40), it plays a role in transcription regulation by catalyzing the monoubiquitination of histone H2B at 'Lys-120' to form H2BK120ub1.

Additional Information

Product Name: UBE2A Rabbit pAb
Catalog No.: Y3202-100
Also Known As: UBE2A; HHR6A; MRXS30; MRXSN; RAD6A; UBC2
Size: 100 µl
Concentration: See labels on tube
Host Species: Rabbit
Isotype: IgG
Reactivity: Human, Mouse
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-152 of human UBE2A.
Swiss Prot. #: P49459
Calculated MW: 17 kDa
Detected MW: 17 kDa
Applications: WB (1:500 - 1:2,000)
IF (1:50 - 1:200)
IP (not tested)
IHC (not tested)
Note: Antibody dilution should be optimized by users.
Purification: Protein A or G affinity purification
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Storage: Store at -20℃. Centrifuge to maximize product recovery.
PDF Data Sheet: PDF DatasheetMSDS
Image(s): (Click image to enlarge)


Shipping Method: Wet ice shipping
References: 1. Koken MH, et al. (1991) Proc Natl Acad Sci USA 88(20), 8865 - 8869.
2. Nascimento RM, et al. (2006) Am J Hum Genet 79, 549 - 555.

Details

UBE2A is a member of the E2 ubiquitin-conjugating enzyme family. Accepts ubiquitin from E1 and catalyzes its covalent attachment to other proteins. In association with the E3 enzyme BRE1 (RNF20 and/or RNF40), it plays a role in transcription regulation by catalyzing the monoubiquitination of histone H2B at 'Lys-120' to form H2BK120ub1.