Additional Information
| Product Name: | Non-cleavable K63 PolyUb Chain (2-10) |
|---|---|
| Also Known As: | N/A |
| Catalog No.: | D2700 |
| Size: | 25 µg |
| Molecular Weight: | N/A |
| Species: | Human |
| Source: | Bacterial recombinant |
| Stock: | 20 mM Tris, 150 mM NaCl, 2 mM βME, 10% Glycerol |
| Concentration: | See tube label |
| Quality Assurance: | ~95% by SDS-PAGE, see datasheet for gel image |
| Storage: | Store at -80°C; avoid multiple freeze-thaw cycles |
| PDF Data Sheet: | PDF Datasheet， MSDS |
| NCBI RefSeq: | N/A |
| Image(s): |  Coomassie stained SDS-PAGE |
| Shipping Method: | Dry ice shipping |
| References: | 1. Hershko A,et al. (1980) Proc Natl Acad Sci USA 77(4), 1783-1786. 2. Pickart CM, (1997) FASEB 11(13), 1055-1066. 3. Hershko A, et al. (1998) Ann Rev Biochem 67, 425-479. 4. Jiang X, et al. (2012) Nature Reviews Immunology 12, 35-48. |
Details
Non-cleavable K63 polyUb chains are made of the Ub(L73P) mutant, this substitution makes the formed polyubiquitin chains to be resistant to the majority of deubiquitinating enzymes.
