Additional Information
| Product Name: | DESI2 Rabbit pAb |
|---|---|
| Catalog No.: | Y9252-100 |
| Also Known As: | DESI2; C1orf121; CGI-146; DESI; DESI1; DeSI-2; FAM152A; PNAS-4; PPPDE1 |
| Size: | 100 µl |
| Concentration: | See labels on tube |
| Host Species: | Rabbit |
| Isotype: | IgG |
| Reactivity: | Human |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-194 of human DESI2 (NP_057160.2). |
| Swiss Prot. #: | Q9BSY9 |
| Calculated MW: | 21 kDa |
| Detected MW: | 21 kDa |
| Applications: | WB (1:500 - 1:2,000) IP (not tested) IHC (not tested) IF (not tested) Note: Antibody dilution should be optimized by users. |
| Purification: | Protein A or G affinity purification |
| Buffer: | PBS with 0.02% sodium azide, 50% glycerol, pH7.3 |
| Storage: | Store at -20℃. Centrifuge to maximize product recovery. |
| PDF Data Sheet: | PDF Datasheet， MSDS |
| Image(s): | (Click image to enlarge)  |
| Shipping Method: | Wet ice shipping |
| References: | 1.Shin EJ, et al. (2012) EMBO Rep 13, 339 - 346. 2. Xie X, et al. (2017) Biochem Biophys Res Commun 488, 291 - 296. |
Details
DESI2 has deubiquitinating activity towards 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. Deubiquitinates 'Lys-48'-linked polyubiquitination of RPS7 leading to its stabilization.
