Additional Information
| Product Name: | BX795 |
|---|---|
| Also Known As: | N-(3-(5-iodo-4-(3-(thiophene-2-carboxamido)propylamino)pyrimidin-2-ylamino)phenyl)pyrrolidine-1-carboxamide |
| Catalog No.: | F6150 |
| Size: | 5 mg |
| CAS: | 702675-74-9 |
| Formula: | C23H26IN7O2S |
| Molecular Weight: | 591.47 g/mol |
| Form: | Powder |
| Quality Assurance: | >98% by HPLC and NMR |
| Source: | Synthetic |
| Storage: | Eligible for room temperature shipping. Store at -20°C upon receiving; protect from air and ligh |
| PDF Data Sheet: | Download PDF datasheet， MSDS |
| Image(s): | N/A |
| Shipping Method: | Room temperature shipping |
| References: | Feldman RI, et al. (2005) J.Biol.Chem. 280 19867. |
Details
BX-795 is an inhibitor of 3-phosphoinositide-dependent kinase 1 (PDK1), as well as other kinases including TANK-binding kinase 1 (TBK1), Aurora B and IkB kinase ε (IKKε). BX-795 prevents TBK1- and IKKε-mediated activation of IRF3 and production of IFN-β.
Solubility:
> 20 mg/ml in DMSO
Solubility:
> 20 mg/ml in DMSO
