Additional Information
| Product Name: | 6xHis-UbE2G1 | ||
|---|---|---|---|
| Also Known As: | UBC7; E217K; UBE2G | ||
| Catalog No.: | C2201 | ||
| Size: | 100 µg | ||
| Molecular Weight: | 19.5 kDa | ||
| Species: | Human | ||
| Source: | Bacterial recombinant | ||
| Stock: | 20 mM Tris, 150 mM NaCl, 2 mM βME, 10% Glycerol | ||
| Concentration: | See tube label | ||
| Quality Assurance: | ~90% by SDS-PAGE, see datasheet for gel image | ||
| Storage: | Store at -80°C; avoid multiple freeze-thaw cycles | ||
| PDF Data Sheet: | PDF Datasheet, MSDS | ||
| NCBI RefSeq: | NM_003342 | ||
| Image(s): | (Click image to enlarge)
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| Shipping Method: | Dry ice shipping | ||
| References: | 1. Watanabe TK, et al. (1996) Cytogenet Cell Genet 74, 146 – 148. 2. Cogen PH, et al. (1996) J Neurooncol 29(1), 103 – 112. 3. Cvekl A Jr, et al. (2004) Eur J Cancer 40(16), 2525 – 2532. 4. Shibata E, et al. (2011) Mol Cell Biol 15, 3136 – 3145. |
Details
UbE2G1 is an E2 enzyme, which is part of the E1, E2, and E3 cascade responsible for ubiquitination of protein substrates. UbE2G1 has been shown to work in conjunction with CRL4, an E3 ligase, to ubiquitinate and degrade Cdt1 after exposure to radiation.
Images:
(Click image to enlarge)
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Coomassie-stained SDS-PAGE Lane 1: Molecular weight markers Lane 2: 5 µg purified 6xHis-Ube2G1 |

