Additional Information
| Product Name: | GST-USP35 |
|---|---|
| Also Known As: | N/A |
| Catalog No.: | H8410 |
| Size: | 25 µg |
| Molecular Weight: | 113.4 kDa |
| Species: | Human |
| Source: | Sf9 cells |
| Stock: | 20 mM Tris, 150 mM NaCl, 2 mM βME, 10% Glycerol |
| Concentration: | See tube label |
| Quality Assurance: | ~90% by SDS-PAGE, see datasheet for gel image |
| Storage: | Store at -80°C; avoid multiple freeze-thaw cycles |
| PDF Data Sheet: | PDF Datasheet， MSDS |
| NCBI RefSeq: | NM_020798.2 |
| Image(s): | H8410 image A. Coomassie stained SDS-PAGE, 0.01 mg GST-USP35. B. DUB activity assay: 10 nM USP35 + 250 nM Ub-Rhodamine 110. Rhodamine 110 fluorescence was monitored by a plate reader with excitation/emission wavelengths at 480/528 nm, respectively. |
| Shipping Method: | Dry ice shipping |
| References: | Liu C. et. al., Oncotarget, 2015, 6, 27891. |
Details
USP35 is a 1018 amino acid cysteine DUB that was found to be overexpressed in certain breast cancers. Its USP domain ranges from amino acids 425 to 926, with cysteine 450 as the catalytic cysteine residue.
