Additional Information
| Product Name: | UBE2L3 Rabbit pAb |
|---|---|
| Catalog No.: | Y3342-100 |
| Also Known As: | UBE2L3; E2-F1; L-UBC; UBCH7; UbcM4 |
| Size: | 100 µl |
| Concentration: | See labels on tube |
| Host Species: | Rabbit |
| Isotype: | IgG |
| Reactivity: | Human, Mouse, Rat |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 73-212 of human UBE2L3. |
| Swiss Prot. #: | P68036 |
| Calculated MW: | 24 kDa |
| Detected MW: | 18 kDa |
| Applications: | WB (1:500 - 1:2,000) IHC (1:50 - 1:100) IF (1:50 - 1:200) IP (not tested) Note: Antibody dilution should be optimized by users. |
| Purification: | Protein A or G affinity purification |
| Buffer: | PBS with 0.02% sodium azide, 50% glycerol, pH7.3 |
| Storage: | Store at -20℃. Centrifuge to maximize product recovery. |
| PDF Data Sheet: | PDF Datasheet， MSDS |
| Image(s): | (Click image to enlarge)  |
| Shipping Method: | Wet ice shipping |
| References: | 1. Moynihan TP, et al. (1996) Mamm Genome 7 (7), 520 - 525. 2. Ardley HC, et al. (2000) Biochim Biophys Acta 1491(1 - 3), 57 - 64. 3. Wenzel DM, et al. (2011) Nature 474 (7349), 105 - 108. |
Details
UBE2L3 is a member of the E2 ubiquitin-conjugating enzyme family. Accepts ubiquitin from E1 and catalyzes its covalent attachment to other proteins. Unlike many E2s that transfer Ub with RINGs, UBE2L3 lacks intrinsic, E3-independent reactivity with lysine, explaining its preference for HECTs.
