Additional Information
Product Name: | 6xHis-Non-cleavable K63 PolyUb Chain (2-4) |
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Also Known As: | N/A |
Catalog No.: | D2800 |
Size: | 25 µg |
Molecular Weight: | N/A |
Species: | Human |
Source: | Bacterial recombinant |
Stock: | 20 mM Tris, 150 mM NaCl, 2 mM βME, 10% Glycerol |
Concentration: | See tube label |
Quality Assurance: | ~95% by SDS-PAGE, see datasheet for gel image |
Storage: | Store at -80°C; avoid multiple freeze-thaw cycles |
PDF Data Sheet: | PDF Datasheet, MSDS |
NCBI RefSeq: | N/A |
Image(s): | Coomassie stained SDS-PAGE |
Shipping Method: | Dry ice shipping |
References: | 1. Hershko A,et al. (1980) Proc Natl Acad Sci USA 77(4), 1783-1786. 2. Pickart CM, (1997) FASEB 11(13), 1055-1066. 3. Hershko A, et al. (1998) Ann Rev Biochem 67, 425-479. 4. Jiang X, et al. (2012) Nature Reviews Immunology 12, 35-48. |
Details
6xHis-non-cleavable K63 polyUb chains are made of the 6xHis-Ub(L73P) mutant, this substitution makes the formed polyubiquitin chains to be resistant to the majority of deubiquitinating enzymes.