TCEP Solution (1M)

TCEP (tris(2-carboxyethyl)phosphine) is a strong reducing agent. Compared to dithiothreitol (DTT) and β-mercaptoethanol, TCEP has the advantages of being odorless, a more powerful reducing agent, an irreversible reducing agent, more hydrophilic, and more resistant to oxidation in air. It is soluble in water and stable at neutral pH. It does not reduce metals used in immobilized metal affinity chromatography such as Ni-NTA resin. TCEP is particularly useful when labeling cysteine residues with maleimides.

TCEP solution (1M) was prepared in water and neutralized with NaOH.

Additional Information

Product Name: TCEP Solution (1M)
Also Known As: Tris (2-Carboxyethyl) phosphine Hydrochloride
Catalog No.: P1021-100
Size: 100 ml
CAS: 51805-45-9
Formula: C9H15O6P ∙ HCl
Molecular Weight: 286.65 Da
Form: Liquid
Quality Assurance: > 95% by HPLC
Source: Synthetic
Storage: Eligible for room temperature shipping. Store at room temperature or 4°C upon receiving
PDF Data Sheet: Download PDF datasheet, MSDS
Image(s): N/A
Shipping Method: Room temperature shipping
References: N/A

Details

TCEP (tris(2-carboxyethyl)phosphine) is a strong reducing agent. Compared to dithiothreitol (DTT) and β-mercaptoethanol, TCEP has the advantages of being odorless, a more powerful reducing agent, an irreversible reducing agent, more hydrophilic, and more resistant to oxidation in air. It is soluble in water and stable at neutral pH. It does not reduce metals used in immobilized metal affinity chromatography such as Ni-NTA resin. TCEP is particularly useful when labeling cysteine residues with maleimides. TCEP solution (1M) was prepared in water and neutralized with NaOH.