Nigericin Sodium Salt

Nigericin sodium salt is an antibiotic derived from Streptomyces hygroscopicus. Functions as an H+, K+, and Pb2+ ionophore. Disrupts mitochondrial membrane potential and activates the NLRP3 inflammasome to induce inflammation.

Additional Information

Product Name: Nigericin Sodium Salt
Also Known As: Antibiotic K178
Catalog No.: F3200-5
Size: 5 mg
CAS: 28643-80-3
Formula: C40H67O11Na
Molecular Weight: 746.94 g/mol
Form: Powder
Quality Assurance: >95% by NMR
Source: Streptomyces hygroscopicus
Storage: Eligible for room temperature shipping. Store at -20°C upon receiving; protect from air and light.
PDF Data Sheet: Download PDF datasheet, MSDS
Image(s): N/A
Shipping Method: Room temperature shipping
References: 1. Eytan, et al (1990) J. Biol. Chem., 22, 12949.

Details

Nigericin sodium salt is an antibiotic derived from Streptomyces hygroscopicus. Functions as an H+, K+, and Pb2+ ionophore. Disrupts mitochondrial membrane potential and activates the NLRP3 inflammasome to induce inflammation.