LY294002

LY294002 is a selective phosphatidylinositol 3-kinase (PI3K) inhibitor. LY294002 inhibit PI3Kα/δ/β with IC50 of 0.5 μM/0.57 μM/0.97 μM, respectively; more stable in solution than Wortmannin, and also blocks autophagosome formation.

Additional Information

Product Name: LY294002
Also Known As: 2-morpholin-4-yl-8-phenylchromen-4-one
Catalog No.: F6110
Size: 5 mg
Molecular Weight: 307.34 Da
Species: N/A
Source: Synthetic
Stock: Powder
Concentration: N/A
Quality Assurance: >99% by HPLC and NMR
Storage: Eligible for room temperature shipping. Store at -20°C upon receiving; protect from air and light
PDF Data Sheet: PDF Datasheet, MSDS
NCBI RefSeq: N/A
Image(s): (Click image to enlarge)


Purity check of Necrostatin-1 by HPLC

Shipping Method: Room temperature shipping
References: 1. Vlahos CJ, et al. (1994) Journal of Biological Chemistry 269 (7): 5241–5248.
2. Blommaart EF, et al. (1997) Eur. J. Biochem. 243: 240–246.
3. Maira SM, et al. (2009) Biochem Soc Trans. 37(Pt 1):265-72.

Details

LY294002 is a selective phosphatidylinositol 3-kinase (PI3K) inhibitor. LY294002 inhibit PI3Kα/δ/β with IC50 of 0.5 μM/0.57 μM/0.97 μM, respectively; more stable in solution than Wortmannin, and also blocks autophagosome formation.

How to use
LY294002 was used at 1-10 uM in cell-based in vitro assays. Images
(Click image to enlarge)


Purity check of Necrostatin-1 by HPLC