LCL161

LCL161 is a potent Smac mimetic that inhibits the inhibitor of apoptosis proteins XIAP, cIAP-1 and c-IAP2. LCL161 induces caspase-dependent apoptosis in various cancer cell lines.

Additional Information

Product Name: LCL161
Also Known As: CAS# 1005342-46-0
Catalog No.: F7171-5
Size: 5 mg
Molecular Weight: 500.63 g/mol
Species: N/A
Source: Synthetic
Stock: Powder
Concentration: N/A
Quality Assurance: >98% by HPLC and NMR
Storage: Eligible for room temperature shipping. Store at -20°C upon receiving; protect from air and ligh
PDF Data Sheet: Download PDF datasheetMSDS
NCBI RefSeq: N/A
Image(s): No
Shipping Method: Room temperature shipping
References: 1. Chen K F., et al. (2012) Biochemical Pharmacology. 84, 268
2. Houghton P J., et al. (2012) Pediatric Blood & Cancer., 58, 636

Details

LCL161 is a potent Smac mimetic that inhibits the inhibitor of apoptosis proteins XIAP, cIAP-1 and c-IAP2. LCL161 induces caspase-dependent apoptosis in various cancer cell lines.