Additional Information
Product Name: | 4-Octyl Itaconate |
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Also Known As: | No |
Catalog No.: | F5270-10 |
Size: | 10 mg |
CAS: | 3133-16-2 |
Formula: | C13H22O4 |
Molecular Weight: | 242.3 g/mol |
Form: | Powder |
Quality Assurance: | >98% by HPLC and NMR |
Source: | Synthetic |
Storage: | Eligible for room temperature shipping. Store at -20°C upon receiving; protect from air and light. |
PDF Data Sheet: | Download PDF datasheet, MSDS |
Image(s): | N/A |
Shipping Method: | Room temperature shipping |
References: | 1. Mills E.L., et al. (2018) Nature, 556, 113. |
Details
4-Octyl Itaconate is a cell-permeable derivative of itaconate, an endogenous metabolite produced during the TCA cycle. 4-octyl Itaconate targets KEAP1 to prevent Nrf2 degradation, thereby exhibiting antioxidative and anti-inflammatory activities.