4-Octyl Itaconate

4-Octyl Itaconate is a cell-permeable derivative of itaconate, an endogenous metabolite produced during the TCA cycle. 4-octyl Itaconate targets KEAP1 to prevent Nrf2 degradation, thereby exhibiting antioxidative and anti-inflammatory activities.

Additional Information

Product Name: 4-Octyl Itaconate
Also Known As: No
Catalog No.: F5270-50
Size: 50 mg
CAS: 3133-16-2
Formula: C13H22O4
Molecular Weight: 242.3 g/mol
Form: Powder
Quality Assurance: >98% by HPLC and NMR
Source: Synthetic
Storage: Eligible for room temperature shipping. Store at -20°C upon receiving; protect from air and light.
PDF Data Sheet: Download PDF datasheet, MSDS
Image(s): N/A
Shipping Method: FedEx
References: 1. Mills E.L., et al. (2018) Nature, 556, 113.

Details

4-Octyl Itaconate is a cell-permeable derivative of itaconate, an endogenous metabolite produced during the TCA cycle. 4-octyl Itaconate targets KEAP1 to prevent Nrf2 degradation, thereby exhibiting antioxidative and anti-inflammatory activities.