6xHis-Ube2Z

Ube2Z is a member of the ubiquitin conjugating enzyme (E2) that specifically works with UBA6 (UBE1L2), but not UBE1, to transfer ubiquitin or the ubiquitin-like protein FAT10 to substrates. It is involved in regulation of apoptosis and protein degradation.

Additional Information

Product Name: 6xHis-Ube2Z
Also Known As: USE1; HOYS7
Catalog No.: C4011
Size: 100 µg
Molecular Weight: 38.2 kDa
Species: Human
Source: Bacterial recombinant
Stock: 20 mM Tris, 150 mM NaCl, 2 mM βME, 10% Glycerol
Concentration: See tube label
Quality Assurance: ~95% by SDS-PAGE, see datasheet for gel image
Storage: Store at -80°C; avoid multiple freeze-thaw cycles
PDF Data Sheet: PDF DatasheetMSDS
NCBI RefSeq: NM_023079.4
Image(s):

Images:
(Click image to enlarge)

Coomassie-stained SDS-PAGE
Lane 1: Molecular weight markers
Lane 2: 5 µg purified 6xHis-Ube2Z
Shipping Method: Dry ice shipping
References: 1. Aichem A, et al. (2010) Nat Commun 1: 13.
2. Gu X, et al. (2007) Mol Biol Rep 34(3): 183-8.
3. Jin J, et al. (2007) Nature 447(7148): 1135-8.

Details

Ube2Z is a member of the ubiquitin conjugating enzyme (E2) that specifically works with UBA6 (UBE1L2), but not UBE1, to transfer ubiquitin or the ubiquitin-like protein FAT10 to substrates. It is involved in regulation of apoptosis and protein degradation.

Images:
(Click image to enlarge)

Coomassie-stained SDS-PAGE
Lane 1: Molecular weight markers
Lane 2: 5 µg purified 6xHis-Ube2Z