Additional Information
| Product Name: | 6xHis-UbE2D4 (UbcH5D) | ||
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| Also Known As: | HBUCE1 | ||
| Catalog No.: | C1700 | ||
| Size: | 25 µg | ||
| Molecular Weight: | 16.6 kDa | ||
| Species: | Human | ||
| Source: | Bacterial recombinant | ||
| Stock: | 20 mM Tris, 150 mM NaCl, 2 mM βME, 10% Glycerol | ||
| Concentration: | See tube label | ||
| Quality Assurance: | ~95% by SDS-PAGE, see datasheet for gel image | ||
| Storage: | Store at -80°C; avoid multiple freeze-thaw cycles | ||
| PDF Data Sheet: | PDF Datasheet， MSDS | ||
| NCBI RefSeq: | NM_015983 | ||
| Image(s): | (Click image to enlarge)
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| Shipping Method: | Dry ice shipping | ||
| References: | 1. Colland F, et al. (2004 Genome Res 14(7), 1324 – 1332. 2. Tokumoto M, et al. (2011) J Toxicol Sci 36(2), 191 – 200. 3. Zhang L, et al. (2011) Genes Dev 25, 1262–1274. |
Details
UbE2D4 is an E2 enzyme, which is part of the E1, E2, and E3 cascade responsible for ubiquitination of protein substrates. UbE2D4 has been linked to cadminum toxicity. It might also play a role in LDL cholesterol receptor ubiquitination in an Idol-dependent fashion.
Images:
(Click image to enlarge)
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Coomassie-stained SDS-PAGE Lane 1: Molecular weight markers Lane 2: 5 µg purified 6xHis-Ube2D4 (UbcH5D) |
