USP21(195-565)

USP21(195-565) contains the catalytic domain of USP21 and it is capable of cleavage of different types of polyubiquitin chains. USP21 can deubiquitinate histone H2A, a specific tag for epigenetic transcriptional repression. It can also cleave Nedd8 conjugates.

Additional Information

Product Name: USP21(195-565)
Also Known As: No
Catalog No.: H7110
Size: 50 µg
Molecular Weight: 41.8 kDa
Species: Human
Source: Bacterial recombinant
Stock: 20 mM Tris, 150 mM NaCl, 2 mM βME, 10% Glycerol
Concentration: See tube label
Quality Assurance: ~ 90% by SDS-PAGE
Storage: Store at -80°C; avoid multiple freeze-thaw cycles
PDF Data Sheet: PDF DatasheetMSDS
NCBI RefSeq: NM_012475.4
Image(s): Images:
(Click image to enlarge)

Coomassie-stained SDS-PAGE
Lane 1: Molecular weight markers
Lane 2: 5 µg purified GST-USP21(195-565)
Shipping Method: Dry ice shipping
References: 1. Gong L, et al. (2000) J. Biol. Chem. 275:14212-14216
2. Ye Y, et al. (2011) EMBO Rep. 12:350-357

Details

USP21(195-565) contains the catalytic domain of USP21 and it is capable of cleavage of different types of polyubiquitin chains. USP21 can deubiquitinate histone H2A, a specific tag for epigenetic transcriptional repression. It can also cleave Nedd8 conjugates.

Images:
(Click image to enlarge)

Coomassie-stained SDS-PAGE
Lane 1: Molecular weight markers
Lane 2: 5 µg purified GST-USP21(195-565)