GST-USP11

Deubiquitinating enzymes (DUBs) are proteases that posses the ability to cleave ubiquitin chains or the isopeptide bond that conjugates ubiquitin with a substrate. Human cells have approximately 100 DUBs that play important roles in regulating various cellular events. Usp11 belongs to the ubiquitin-specific protease family. It helps in repairing DNA damage. It has been found to interact with RanBPM, a RanGTP-binding protein.UHX1

Additional Information

Product Name: GST-USP11
Also Known As: UHX1
Catalog No.: H6110
Size: 25 µg
Molecular Weight: 109.8 kDa
Species: Human
Source: Sf9 insect cells
Stock: 20 mM Tris, 150 mM NaCl, 2 mM βME, 10% Glycerol
Concentration: See tube label
Quality Assurance: ~85% by SDS-PAGE, see datasheet for gel image
Storage: Store at -80°C; avoid multiple freeze-thaw cycles
PDF Data Sheet: PDF DatasheetMSDS
NCBI RefSeq: NM_004651
Image(s): No
Shipping Method: Dry ice shipping
References: 1. Wanson DA, et al. (1996) Hum Mol Genet 5, 533 – 538.
2. Ideguchi H, et al. (2002) Biochem J 367(Pt 1), 87 – 95.
3. Reyes-Turcu FE, et al.(2009) Annu Rev Biochem 78, 363 – 397.

Details

Deubiquitinating enzymes (DUBs) are proteases that posses the ability to cleave ubiquitin chains or the isopeptide bond that conjugates ubiquitin with a substrate. Human cells have approximately 100 DUBs that play important roles in regulating various cellular events. Usp11 belongs to the ubiquitin-specific protease family. It helps in repairing DNA damage. It has been found to interact with RanBPM, a RanGTP-binding protein.