Additional Information
Product Name: | GST-JOSD2 | ||
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Also Known As: | No | ||
Catalog No.: | H1900 | ||
Size: | 50 µg | ||
Molecular Weight: | 21.7 kDa (no GST tag) | ||
Species: | Human | ||
Source: | Bacterial recombinant | ||
Stock: | 20 mM Tris, 150 mM NaCl, 2 mM βME, 10% Glycerol | ||
Concentration: | See tube label | ||
Quality Assurance: | ~ 90% by SDS-PAGE | ||
Storage: | Store at -80°C; avoid multiple freeze-thaw cycles | ||
PDF Data Sheet: | PDF Datasheet, MSDS | ||
NCBI RefSeq: | NM_001270639.1 | ||
Image(s): | H1900 Image:
(Click image to enlarge)
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Shipping Method: | Dry ice shipping | ||
References: | 1. Deki T, et al. J Biol Chem. 288(24):17145-55. |
Details
JOSD2 (Josephin-2) is a member of the Machado-Joseph Domain (MJD) deubiquitinating enzyme family. Other family members include: Ataxin-3, Ataxin-3L, and JOSD1. JOSD2 preferentially cleaves K63-linked ubiquitin chains, with much weaker activity toward K48-linked ubiquitin chains in vitro.