GST-DESI-2

DESI-2 (desumoylating isopeptidase 2, also called Permuted Papain fold Peptidases of DsRNA viruses and Eukaryotes (PPPDE1)) and DESI-1 (also called PPPDE2) contain a Ub-binding domain and a cysteine protease domain. They catalyze both desumolyating and deubiquitinating activities.

Additional Information

Product Name: GST-DESI-2
Also Known As: PPPDE1
Catalog No.: H8970
Size: 50 µg
Molecular Weight: 21.4 kDa (no GST tag)
Species: Human
Source: E. coli
Stock: 20 mM Tris, 150 mM NaCl, 2 mM βME, 10% Glycerol
Concentration: See tube label
Quality Assurance: ~90% by SDS-PAGE, see datasheet for gel image
Storage: Store at -80°C; avoid multiple freeze-thaw cycles
PDF Data Sheet: PDF DatasheetMSDS
NCBI RefSeq: NM_016076.4
Image(s): H8970 image

Coomassie stained SDS-PAGE of 5 ug GST-DESI-2.
Shipping Method: Dry ice shipping
References: 1. Iyer LM., et al. Cell cycle 3 (2004) 1440e1450.
2. Shin EJ., et al. EMBO Rep. 13 (2012) 339e346.
3. Gillies J., et al., EMBO Rep. 13 (2012) 284e285.
4. Xie X., et al. Biochem Biophys Res Commun. 2017 488(2):291-296.

Details

DESI-2 (desumoylating isopeptidase 2, also called Permuted Papain fold Peptidases of DsRNA viruses and Eukaryotes (PPPDE1)) and DESI-1 (also called PPPDE2) contain a Ub-binding domain and a cysteine protease domain. They catalyze both desumolyating and deubiquitinating activities.