6xHis-AMSH

AMSH belongs to the JAMM family of deubiquitinases that are Zn2+-dependent metalloproteases. AMSH is an endosome-associating DUB that regulates endosomal sorting by deubiquitination. SMSH specifically cleaves lysine 63-polyubiquitin chains.

Additional Information

Product Name: 6xHis-AMSH
Also Known As: STAM-binding protein
Catalog No.: H4500
Size: 50 µg
Molecular Weight: 48 kDa
Species: Human
Source: Bacterial recombinant
Stock: 20 mM Tris, pH 7.1 at 37 0C, 150 mM NaCl, 2 mM βME, 10% Glycerol
Concentration: See tube label
Quality Assurance: ~ 90% by SDS-PAGE, see datasheet for gel image
Storage: Store at -80°C; avoid multiple freeze-thaw cycles
PDF Data Sheet: PDF DatasheetMSDS
NCBI RefSeq: AAD05037
Image(s): Images:
(Click image to enlarge)

Shipping Method: Dry ice shipping
References: 1. McCullough, J., et al, J. Cell Bio., 2004, 166, 487.
2. Sato, Y., et al. Nature, 2008, 455, 358.

Details

AMSH belongs to the JAMM family of deubiquitinases that are Zn2+-dependent metalloproteases. AMSH is an endosome-associating DUB that regulates endosomal sorting by deubiquitination. SMSH specifically cleaves lysine 63-polyubiquitin chains.

Images:
(Click image to enlarge)